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Whilst great advancements have been made over the last century with regard to understanding the regulation of metabolic homeostasis which has yielded new therapeutic options for diseases such as T2D, it is unlikely that highly desirable more efficacious treatments will be developed for metabolic disorders until the complex systemic regulation of metabolic homeostasis becomes more intricately understood

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Whilst these effects might appear complementary, the combined hormonal and metabolic signalling could produce effects that are difficult to monitor or predict without clinical oversight

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Antiemetic medication can be used to counter the nausea if it is severe or there is vomiting but antiemetic medication should only be used if necessary and should not be used on a continual basis